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Melanoma is amongst the most aggressive cancers. Although early stages of melanoma can be removed by surgery with high patient survival prices, metastatic melanoma has poor prognosis. Regardless of current progress in the remedy of late-stage melanoma, and in specific, the advance in improvement of novel targeted therapy and immunotherapy approaches, the all round outcome of individuals with metastatic melanoma remains poor.1 The median survival period of these sufferers is about 6 to 10 months, and t.
